Second, by exploring the virus-human protein-protein interaction network, we found that viruses of different types can target the same human proteins.
Moreover, the method points to a new direction where the functional relationships between viruses and hosts can be used to explore the virus relationships on a systematic level.
The stratified models were developed to explore the virus-specific host patterns and to minimize biases related to variability in research effort among viruses.
Munson-McGee et al. combined single-cell sequencing with environmental metagenomics to explore the virus-host interactions in a Yellowstone National Park hot spring microbial community (Munson-McGee et al., 2018).
To explore the virus-host interaction and develop the infectious clone-based PRRSV vaccine, the genetically-marked infectious clone of North American Type II PRRSV is needed.
By exploring the way the virus gets this done, they may also discern ways to prevent the virus from disrupting chromatin, ending a herpesvirus reactivation before it can produce a new outbreak of disease.
Plant viruses have been used as model systems for exploring the mechanisms of virus evolution [1], [2].
Building on their success in vaccination, many groups are now exploring the use of viruses as anticancer agents.
To explore the swinepox virus (SPV) as a potential live vector for immunization, a vector was developed for the construction of a recombinant SPV carrying foreign genes.
More studies are planned to explore the XMRV virus and CFS.
Since the majority of known plant viruses are exclusively vector-transmitted [9], examination of insect vectors presents a unique avenue for exploring the diversity of plant viruses.
