To our knowledge this is the first empirical research study exploring investigator-initiated trial implementation in low-income and middle-income countries.
We explored how investigators of ongoing or planned trials respond to the publication of a trial stopped early for benefit addressing a similar question.
To the extent that such effect modification has been previously explored, some investigators found the higher risk of wood dust related lung cancer among smokers than among non-smokers [ 6, 17, 33].
Lastly, we show that cardiac differentiation prior to transplantation can prevent teratoma formation, which remains a major safety concern for investigators exploring the therapeutic uses of hESCs.
The success of this follow-up of an Indigenous birth cohort may encourage other investigators exploring causal pathways of chronic adult disease in indigenous populations.
Investigators exploring the genomic architecture of TNBCs discovered a spectrum of somatic mutations; however, only a few loci are recurrently mutated with significant frequency [ 5, 6].
These genes (connected with a CX43 deficiency) could also represent helpful markers for investigators exploring the molecular mechanisms of human male sterility.
The candidate genes could represent helpful markers for investigators exploring human testicular biopsies from patients showing corresponding spermatogenic deficiencies and for studying the molecular mechanisms of human male sterility.
Large-scale nucleic acid arrays have become very useful tools for investigators exploring differences in gene expression between cell types, stages of differentiation, and cellular responses to stimuli [ 3].
Federal investigators are exploring whether Mr. Jackson steered government contracts to friends in New Orleans and the Virgin Islands.
