We therefore explored in two ongoing studies, the National Heart ,Lung, and Blood Institute NHLBI Family Heart Studydy (FHS) and the Bogalusa Heart Study (BHS), the racial effect on LTL.
An alternative approach, currently explored in our ongoing program together with Novo Nordisk (http://www.novonordisk.com) and Lund University (Sweden), is to develop fully functional glucose-responsive β-cells and in the end to transplant these cells to patients using an encapsulation technique.
However, the lower rSBA-MenC GMTs may have an impact on antibody persistence and this is being explored in an ongoing extension study (NCT01266993).
In the meantime, it is worth noting that valproic acid has been suggested to act as pharmacological chaperone for unfolded proteins and is being explored in an ongoing clinical trial in patients with autosomal dominant retinitis pigmentosa (http://clinicaltrials.gov/ct2/show/study/NCT01233609).gov/ct2/show/study/NCT01233609
The positive results will be further explored in ongoing phase III clinical trials to fully understand the safety and efficacy of GPR40 agonists in the treatment of type 2 diabetes.
In this research, a combined approach utilizing principles of sustainable manufacturing and systems thinking (in the form of systems dynamics) is explored, which leads to development of a conceptual model being explored in ongoing research.
Nevertheless, although there are no indications of a statistically significantly increase in risk of cancer with dapagliflozin and it appears that early tumor diagnosis may be attributable to detection bias rather than as a result of a causal relationship, this issue, specifically regarding the risk of bladder cancer, will be further explored in ongoing dapagliflozin trials [ 71, 78].
The role of nVNS in migraine therapy is being further explored in ongoing large-scale, randomised, sham-controlled trials with long-term follow-up.
The use of NOACs is currently not recommended by international consensus guidelines but is now being explored in ongoing clinical trials.
Gene therapy provides powerful new approaches to curing a large variety of diseases, which are being explored in ongoing worldwide clinical trials.
