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Currently only few studies have explored disease characteristics, treatment and outcome of NASH-related HCC.
The emergence of network medicine [ 1] has explored disease complexity through the systematic identification of disease pathways and modules.
A recent study has explored disease progression while measuring lung function and peripheral skeletal muscle dysfunction (by determining skeletal muscle function and fibre-type distribution) over time in the same animal [ 75].
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It seems only appropriate that approaches derived from his inventions are now being used to explore disease.
Chapter 5 (Richard Kock and colleagues) explores disease control.
This model of HIV-1 infection can be further extended to explore disease behaviour to get deeper insights.
The chapter explores disease management and Dyer's proposed business model.
Further, we explore disease subtype specificity and functions of selected expressed pseudogenes.
Initially, heteroplasmic mice were created to explore disease pathogenesis and mitochondrial dynamics in an in vivo system.
Given the seminal technical progresses achieved in the last few years, it may be ready to tackle even greater challenges, namely exploring disease mechanisms.
While Aβ and tau represent the two key pathological mediators of disease, other aspects of this multifaceted disease (e.g. oxidative stress, calcium-mediated toxicity, and neuroinflammation) are being unraveled, with the hope to develop a more comprehensive approach in exploring disease mechanisms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com