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Currently CA4P is further explored as single agent in phase-II studies in patients with advanced anaplastic thyroid cancer.
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Pracinostat is an oral pan-HDACi with favorable pharmacokinetics and good tolerability in patients, which is currently explored as a single agent in multiple Phase II clinical studies, for solid tumors as well as myelodysplastic syndrome, AML and myelofibrosis.
According to the result, the total computational cost was drastically reduced while the same optimum solution can be explored as a single-fidelity optimization.
This approach has been used to discriminate DNA length and in some cases even the type of DNA bases based on transit time and is beginning to be explored as a single-molecule DNA sequencing tool.
Engineered ion channels have been explored as highly sensitive single molecule sensors.
The next dose level down (202 mg m−2) might have been explored as a potential single-agent phase II dose.
A series of detection methods for SNPs has been explored, such as single-strand conformation polymorphism (SSCP) and invader assay with dual-color fluorescence polarization detection.
These results showed the feasibility of capturing bone scintigraphy data as a single quantitative measure and thereby allowing bone scans to be explored as imaging biomarkers.
Graphene, a single layer of carbon atoms densely arranged into a honeycomb pattern, has been widely explored as a newly alternative to plasmonic material [18, 19].
Thus, mtDNA in blood may be explored as a sensitive surrogate to systemic oxidative stress by simultaneous analysis of multiple end-points in a single test.
As discussed previously, firstly we explored the single classifier approach, according to which a single classifier is being used for the management of all the cases.
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CEO of Professional Science Editing for Scientists @ prosciediting.com