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The Xenopus pronephros and zebrafish pro- and mesonephric kidneys, therefore, are increasingly being explored as model systems for human kidney disease (Drummond, 2005; Ebarasi et al., 2011).
Two-dimensional hydrogels with topographical features such as grooves and pits thus have been explored as model systems to study such cellular behavior.
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Over the last decade chelate-tethered nucleobases have been explored as models for metal ion DNA interactions as well as to extend the molecular architecture of metal complexes capable of base-pair hydrogen bonding.
Self-assembled monolayers (SAMs) of ω-substituted alkanethiols on gold have been explored as well defined in vitro model surfaces for the investigation of neuronal growth and function.
Gold nanoparticles of 2-nm core size are linked by 1,9-nonanedithiolates into a network thin film on planar substrate, and are explored as a model system of core-shell nanostructured catalysts.
Phospholipid, a main component of cell membrane, has been explored as a model system of the cell membrane and temporary scaffold materials in recent studies.
So far, N. benthamiana has been successfully explored as a model for expression of therapeutic proteins, such as antibodies [20].
In addition, other mechanisms for collective movement will need to be explored as the model is expanded and refined.
Genome of Cryptococcus, rich in short introns, is being explored as a model to understand evolutionarily conserved mechanisms of splicing [ 38].
The Ms2Yah mice should be further explored as a model of Hsa21 terminal deletion for which little consequence has been described so far (Lyle et al. 2009; Lindstrand et al. 2010; Roberson et al. 2011).
To address this issue, we directly assessed the human response to phthalate exposure using a cross-species xenotransplantation approach, which has previously been explored as a model of testicular development and function in rodents (Kuopio et al. 1989), primates (Ehmcke et al. 2011), and humans (Mitchell et al. 2010).
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