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To explore the differentiation markers for detecting germ cells differentiated from ES cells, the expression of various germ cell marker genes was examined in tissues and ES cells of the cynomolgus monkey (Macaca fascicularis).
The aim of the study was to explore the differentiation potential, expansion and growth kinetics of the human adipose derived stem cells (hADSCs) in alginate microspheres in comparison to chondrogenesis from the cartilage tissue.
To explore the differentiation capacity of MOSJ-Dkk1 and MOSJ-pLenti cells in vitro, we performed alkaline phosphatase (ALP) assays on cultures in the presence of osteogenic factors, ascorbic acid and β-glycerophosphate.
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This study explores the differentiation potential of hMSC in a tissue-specific microenvironment simulated in vitro.
We next explored the differentiation potential of the cells into other lineages.
Taken together, these results indicate that this LSPAD method is reliable for exploring the differentiation of the protein abundances between non-disease and disease serum.
In light of recent work exploring the differentiation potential of hMSCs beyond the OS, AD, and chondrogenic lineages, it would be interesting to compare Vmem changes in neural or myogenic hMSC differentiation to the hyperpolarization reported in neural precursors, myoblasts, and OS- and AD-differentiated hMSCs.
In this study, we explored the differentiation potential of mouse induced pluripotent stem (iPS) cells towards male germ cells.
Exploring the differentiation potential of a haploid karyotype highlights developmental constraints imposed by evolutionary adaptations specific for the mammalian genome namely genomic imprinting and X chromosome inactivation.
The paper by P. Li et al. explored the differentiation potential of mouse iPS cells towards male germ cells; the expression of marker proteins, including MVH, CDH1, and SCP3, was remarkably increased, and mRNA expression of Stra8, Odf2, Act, and Prm1 was upregulated in iPS cells by retinoic acid or testosterone induction.
Since mammospheres are composed of undifferentiated mammary cells, we have utilized three-dimensional Matrigel cultures to explore the morphogenic differentiation potential of these cells.
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