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Capecitabine appeared to have definite, albeit limited, activity in advanced pancreatic cancer and it was therefore decided to explore combination treatment with gemcitabine as the next phase of development.
Explore combination products, too.
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In the workflow we developed above, we combined the functionality of Cytoscape's Select panel with setsApp to explore combinations of sets of genes based on shared properties.
These professionals depend on the execution of large sets of computational jobs that explore combinations of parameter values.
We explore combinations of these options in development test experiments.
Multivariable logistic regression models were generated to explore combinations of variables associated with different MRC thresholds.
Our aim is to explore combinations of feature selection methods with various alternate model fitting techniques in constructing assays with high responder versus non-responder classification accuracy.
In this regard, it will be important to explore combinations of HDAC inhibitors with differing HDAC specificity and identify possible synergistic effects.
There is a need for strategies with anti-EGFR agents alone or in combination with conventional chemotherapies and to explore combinations with other molecularly targeted therapies such as angiogenesis inhibitors.
A feature selection methodology that includes a genetic algorithm search coupled to a logistic regression classifier and forward and backward selection strategies was used to explore combinations of features.
While most studies examine the theoretical properties of transgenic constructs embodying single drive mechanisms [ 7- 13] 13], the observation that "most of them have specific characteristics that make them less than ideal" led Huang et al. 2007 [ 14] to explore combinations.
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