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No confirmatory statistical tests were performed, but 95% confidence intervals and p values were calculated for exploratory treatment group comparisons.
In conclusion our pilot study supports the feasibility of montelukast as initial exploratory treatment of patients with chronic cough in the primary care setting.
The nature of this innovative exploratory treatment study necessarily provides limits on the effective sample size, limiting the number of smokers that can be recruited, complete instruments, and participate in the intervention.
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The exploratory 'no treatment' arm used to assess the public health benefit of patients beginning treatment for alcohol dependence may not be an accurate representation of the natural evolution of the disease when untreated.
Some recent reports, however, showed that laparoscopy offers exploratory possibilities, treatment options and enhanced recovery in this particular setting of prompt management [1, 8, 10, 11, 14].
In the current exploratory study, treatment with nintedanib provided an investigator-assessed 9-month PFS and median PFS and OS similar to sunitinib.
The propensity score-matched subgroup, in which exploratory between-treatment comparisons were made, included about half of the original study population and was based on baseline demographic and clinical variables (key characteristics of the total study population are summarized in Table 1).
The goal of this study was to perform an exploratory analysis of treatment costs for open tibial fractures and define strategies in order to reduce these costs.
The rotating rod apparatus (Columbus Instruments) was used to measure the ability of the animals to improve their locomotor skills with training [39]. 1 day before, 1 day after and 4 weeks after TMZ/sham treatment exploratory activity was evaluated using an open field test [40].
Table 3 shows the subgroup exploratory analysis by treatment according to TS status.
However, they are useful for exploratory analysis of treatment effects in the subgroups and between subgroup effects.
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