In fact exploratory therapies include administering carbon monoxide to the patient using carbon monoxide-releasing molecules.
This is consistent with our approach to include all participants and interventions for tinnitus, including exploratory therapies recruiting non-clinical groups.
Therefore, in an attempt to predict preferential benefit from combined AKT inhibitor/trastuzumab therapy, exploratory biomarker analyses may need to consider the polygenic nature of trastuzumab resistance and assess multiple aberrations in the HER2 signaling pathway in each tumor.
In an exploratory analysis, poor therapy response, and especially response to prednisone was the main reason for classification of BCL2−938 CC patients into the high-risk group, although their overall outcome was not worse than the outcome of patients belonging to standard-or medium-risk groups.
"But managed care wouldn't pay for such 'unfocused' or 'exploratory' therapy discussions," Dr. Shulman said.
She suggested that a body of medical women might cooperate in a study of one specific aspect of cancer therapy; an exploratory committee was immediately formed, with Dr. Chambers and four gynecological surgeons as members.
In conclusion, the data from this large exploratory study suggest that maintenance therapy with pegaptanib may provide an alternative to prolonged non-selective VEGF inhibition by holding visual gains after induction.
Previous exploratory work suggests that cognitive behavioural therapy (CBT) is acceptable and effective for women with HF/NS during natural menopause and following breast-cancer treatment.
Table 1 Recommendations for diagnostic reporting of post-radioembolization 90 Y PET/CT Item Recommendation Continuity of care Post-radioembolization 90Y PET/CT is best reported by the same attending nuclear medicine physician who has followed through the entire planning-therapy continuum from exploratory angiography, predictive dosimetry, to 90Y radioembolization.
Coupled with an incomplete understanding of the relationship between clinical characteristics and prognosis in HER2-positive MBC, the factors that predict outcome or response to HER2-targeted therapies are mostly exploratory.
As a result, patients operated at the very limits of their endurance, and all collaboration between HCPs and patients was exploratory, i.e., as PI therapy was extremely new, the clinicians' experience was severely limited and related literature remained scant.
