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Exploratory objectives included investigation of an extensive set of physiological, psychosocial, dietary, and behavioral variables as moderating and/or mediating variables and/or secondary outcomes.
Secondary and exploratory objectives include determination of PFS, OS in molecular subgroups (defined by EGFR and KRAS mutation status, amplification or overexpression of MET, and serum hepatocyte growth factor), and safety.
Exploratory objectives include assessment of the quality of life through multiple lines of treatment, comparison of the efficacy between Asian and non-Asian patients, and correlation of biomarkers with efficacy outcomes, disease response, and adverse events.
Other exploratory objectives of the mission include the study of the galactic and local extragalactic magnetic field; the detection of high-energy gamma rays and neutrinos, and tests of relativity and quantum gravity effects at extreme energies.
Exploratory objectives include comparison of disease control rate after the end of subsequent second-line treatments, comparisons of vaccine immune responses, comparison of survival rate at 12 months in patients with vaccine-induced immune response detected after the second and sixth injections, identification of biomarkers on lymphocytes and on tumors, and comparison of safety and tolerability.
Additional exploratory objectives included evaluating provider type and patient-provider relationship as a factor for change in PIM prescribing.
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Our secondary exploratory objective was to investigate the effects of pepsin exposure on the morphological properties of collagen in the lamina propria.
A second exploratory objective of this study was to compare potential differences in core symptoms between BD and healthy control (HC) groups.
As an exploratory objective was the assessment of the impact of the intervention in the mother on the health of the child during the first year of life.
Inspiratory capacity was investigated as an exploratory objective.
Pre-planned exploratory objective: EGFR mutation analysis in matched tumour and plasma samples.
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