Exact(3)
Although the present 14-day-treatment period, showed that OSU6162 was safe and well tolerated, this exploratory human laboratory study was not designed to evaluate the efficacy of OSU6162 to affect alcohol consumption.
The present Phase II exploratory human laboratory study investigated to our knowledge for the first time the effects of OSU6162 on cue- and priming-induced craving in alcohol dependent individuals.
95 An exploratory human clinical study has shown some recent promise for a combination of baclofen, naltrexone, and sorbitol (PXT3003), showing early evidence for consistent improvement beyond stabilization.
Similar(54)
However, to the best of our knowledge, no techniques have been proposed for exploratory, human-guided qualitative analysis of insect motion aside from simple observations with the naked eye.
Finally, a European strategy leading to a potential European participation in future human exploratory missions has been recommended.
Human exploratory missions cannot be safely performed without a substantial reduction of the uncertainties associated with different space radiation health risks, and the development of effective countermeasures.
A roadmap in the field of health care has been elaborated for a future European participation strategy towards human exploratory missions taking into account preparatory activities, such as analogue situations and ISS opportunities, and potential terrestrial applications and benefits.
We are now focusing on translating the algorithms in a stepwise fashion after instrumentation and agents are introduced into a human exploratory study.
[11C]KTP-Me is washed out from normal tissues, leading to the present first-in-human exploratory study.
When this is the case, it is of course critical that they are evaluated beyond exploratory first-in-human studies.
Although the FDA in their ground-breaking "Critical Path Initiative" points to the need for more exploratory studies in humans, the existing dogma followed by most regulatory bodies is to avoid all potential risks if benefits are difficult to assess in the short term.
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