Exact(1)
This article demonstrates that clinical trial design tools that would allow the medical community to draw confirmatory and not just exploratory conclusions from specific subgroup evaluations are available to methodologists.
Similar(59)
Conclusions: In exploratory analyses of a randomised trial in patients with septic shock, we observed no mortality benefit in any subgroups of transfusion at a haemoglobin threshold of 90 g/dl vs. 70 g/dl.
Since this was a correlational study, we will consider our conclusions as exploratory but very relevant to infer management implications of interest in Mediterranean areas.
Although it should be noted that this was an exploratory study and the conclusions should be interpreted cautiously due to the heterogeneous cell population from the nasal biopsy and the small amount of material obtained, which did not allow for any validation of gene expression differences.
Our findings are exploratory rather than causal conclusions.
Hence our conclusions are exploratory and need validation in a randomized controlled trial.
Data from such a trial can thus at best support exploratory analysis and yield conclusions of the form: 'the model found to be the best fit to the data in this case was…' rather than being confirmatory.
90 Although the number of individuals tested in the present study does not encourage generalized conclusions, our exploratory study strongly suggests that the CANTAB test results in isolation may improve the signal-to-noise ratio when distinguishing the performance of subgroups both in young adults and the elderly better than language tests do.
In conclusion, this exploratory post hoc analysis demonstrated that the ION was associated with fewer adverse clinical events than the TAXUS Liberté because of decreased non Q-wave MI.
In conclusion, this exploratory study found that the use of an allostatic, noninvasive, closed-loop, acoustic stimulation neurotechnology, HIRREM, by a series of young athletes with PPCS, was associated with significant reductions in clinical symptoms; improvements in autonomic cardiovascular regulation; return to exercise, recreational, and academic activities; and a high rate of return to play.
In conclusion, this exploratory study provides some new evidence that patients with bilateral glaucoma exhibit different eye movement behaviour compared to visually healthy subjects when viewing a driving scene.
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