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To investigate whether there is a functional link between TMSB15A mRNA levels and response to chemotherapy, exploratory cell culture experiments were conducted.
In addition, controlled delivery may be beneficial in various in vitro assays, such as high-throughput drug screening or exploratory cell biology experimentation.
The presence of these RasGAPs in organisms that display strikingly similar forms of circular ruffling suggests the hypothesis that NF1 and MNF evolved together to control the movements of the exploratory cell projections used in very early eukaryotes during feeding (Boschek et al., 1981; John et al., 1984; Hacker et al., 1997; Cavalier-Smith, 2013).
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It should be expected that these exploratory cells remain in communication with their neoplastic clonal lineages at their site of origination and well as others dispersed throughout the entire macroorganism.
Recently, local exploratory SVZ cell motility was seen in nestin-GFP and Gad-GFP mice [7].
Distinctive tip cell exploratory behavior, adhesion, and basement membrane clearing underlie target recognition and dynamic interactions.
Here we found that EGFrlow cells are more exploratory and slower than motile cells which do not express EGFr.
Similar to the Nitz & McNaughton (2004) study, we measured the average firing rate of cells during exploratory periods, and observed an increase in pyramidal cell firing rates in novel environments as compared with familiar ones, while the firing rate of interneurons was unchanged.
This analysis of wild type genotypes reveals different phases of filopodial exploratory behavior in R cell growth cones.
In an exploratory attempt, SH-SY5Y cells (n = 5) and hippocampus tissue (n = 3) were treated with either T or Org4049 at 10−6 M and 10−8 M, respectively (Fig. 3).
Here, we used 8 Hz stimulation, because the spectral power of network activity recorded from dentate gyrus granule cells during exploratory behaviour was found to be exactly in the range of 8 Hz (Fig. 4A).
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