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Further exploration of the reported zebrafish model system may elucidate the consequences of reduced nutrient availability during embryogenesis.
Furthermore, exploration of the reported subgroups for these studies also failed to demonstrate any possible interaction between treatment and disease severity that could have contributed to the lack of observed efficacy (Fig. 2).
16 An in-depth exploration of the reported experiences of a small number of women with HIV in a postnatal care setting is not generalisable to other groups and settings (eg, HIV-negative women, women without children).
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After accounting for months with fewer than 31 days, further exploration of the data on reported calf birth dates indicated a notable tendency to report the 1st, 10th and 20th of the month.
Future work could explore this further by collecting time in unit as well as time in organization and probing these separately, thus disaggregating temporal effects of unit-and organization-level patient safety climate processes and leading to a richer exploration of the tenure associations reported in this study.
For effective interventions to make their way into practice, clinicians need to know the details of the intervention and be able to answer the question of 'How do I actually provide the intervention that this review is recommending?' Exploration of the completeness of reporting of interventions in systematic reviews has received little attention.
For a distributed exploration of the state space, we report the lessons learned from using different partitioning schemes, including Holzmann and Bosnacki's [G. Holzmann and D. Bosnacki. The design of a multi-core extension of the Spin Model Checker. IEEE Trans. on Software Engineering, 2007.
The development of the framework has been preceded by an intensive exploration of the literature, which we report on in our methods section.
A preliminary exploration of the patterns of drift is reported in the Supplementary Material.
In addition, there is limited reported exploration of the appropriateness of care to patients who form the majority of the workload – the patients consulting with acute, undifferentiated conditions, or comparison with care provided by doctors for the same case mix of patients.
Also helpful in detecting dissemination bias are, for example, the exploration of selective reporting of outcomes as part of the detailed risk of bias evaluation within systematic reviews, 24 and the graphical (eg, funnel plots) and statistical assessment of potentially selective publication of whole studies (eg, Egger's test).
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