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Further study of the variant in other patient cohorts and exploration of the functional effects of TM6SF2 on inflammatory response will be needed to address this point.
Hence, the HuAChE stereoselectivity provides a sensitive tool in the in depth exploration of the functional architecture of the active center.
The study demonstrates a model of MEMRI-functionalized DBS based on functional neural interface engineering and controllable delivery technology, which can be utilized in more detailed exploration of the functional anatomy in the treatment of neurodegenerative diseases.
Results presented here indicate that exploration of the functional roles of Drosophila octopaminergic neurons provide a useful system to ask how neuromodulatory inputs at the cellular level alter the properties of a social behavior network.
Here, we report an in-depth exploration of the functional and regulatory networks associated with PIP gene expression in breast carcinoma cell lines using DNA microarray-based gene expression profiling techniques.
Structural modeling supported by experimental probing has offered ideas based on the symmetry features of the molecules in this family [21], [22], and the powerful approach of computational simulation using high resolution structural information was applied to the exploration of the functional mechanisms of proteins with a LeuT-like structure fold (e.g., see [10], [16], [23] [33].
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Exploration of the underlying functional annotations of trait-associated loci has thrown some light on their potential roles in pathogenesis.
Specifically, the deep tissue penetration of near-infrared light, coupled with its sensitivity to hemodynamic signatures has led to novel studies in critical care monitoring [ 1– 5] and to exploration of the normal functional responses of specific brain networks [ 6– 10].
Further studies will be focused on exploration of the possible functional differences between TACC1 isoforms, definition of cell populations that express Tbdn-1 acetyltransferase and investigation of its possible role in tumour angiogenesis.
This allows exploration and differentiation of the functional consequences of the enzymatic versus receptor function of the Na+/K+ ATPase.
Exploration of the biochemical and functional properties of vSMCs provides important insight into the potential pathogenic mechanisms of vascular fibrosis.
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