In addition to a strategic and integrated knowledge-based exploitation of omics tools and the introduction of the AOP concept, we further propose a strong focus on human-specific models.
This allows exploitation of the tool in a simple and efficient way in comparison to the currently distributed approach.
Finally, we note the lessons learned, the resources needed, and the types of end-users, scientists and mediators required to ensure effective communication, technical development and exploitation of spatial modelling tools for integrated environmental decision-making.
However, in recent years, following the achievement of the human genome sequencing, the exploitation of molecular biology tools revealed that specific antioxidant compounds modulate various cellular functions, acting not only as radical scavengers, but also as genes and enzyme expression regulators (Knasmüller et al., 2008).
Exploitation of this clinical tool in the rodent has been described [ 31] but remains controversial [ 16, 32].
The full exploitation of Life Cycle Assessment tools within frameworks for production process development still needs significant research efforts.
A wider acceptance of mobile agents would be facilitated with the exploitation of suitable methodologies and tools which fully support their development lifecycle.
The methodology of course replication (T1 and T2 activities) will allow the exploitation of NECOBELAC resources and tools also beyond the NECOBELAC Project conclusion (January 2012).
Meeting them will require more thoughtful model formulation, better exploitation of currently available statistical tools and perhaps the development of new (most likely approximate) methods of inference.
To facilitate the access and exploitation of TCGA data, several tools have been developed to compare and to explore the different levels of data, facilitating the discovery of associations and correlations, as well as allowing ascertaining the significance of certain alterations in cancer [ 5– 7].
