For example exploitation-dependent immunopathology, could select for decreased virulence (Day et al. 2007), by decreasing parasite immunogenicity and/or replication rate.
Such methods also enable identification of exploitation-dependent versus exploitation-independent immunopathology, which is critical to predicting evolutionary trajectories (Day et al. 2007).
The extent to which malaria in the laboratory represents malaria in the field, plus the relative importance of inflammation- versus exploitation-dependent immunopathological virulence, will determine whether we expect increased or decreased ESS virulence due to immunopathology.
For example, whereas virulent clone AJ causes RBC loss via both exploitation-dependent and -independent mechanisms, virulent clone BC appears to cause virulence independent of exploitation, but strongly dependent upon the inflammatory response induced (for example, 3.3 billion RBCs were lost for every log increase in picograms of pro-inflammatory cytokines per milliliter of plasma).
Secondly, the DE-based parallel evolution mechanism and framework is applied to perform effective exploration, and a simple but efficient local search developed according to the landscape of FSSP is applied to emphasize problem-dependent local exploitation.
The recent development of technologies designed to access this wealth of genetic information through environmental nucleic acid extraction has provided a means of avoiding the limitations of culture-dependent genetic exploitation.
Brunei's economy is almost totally dependent on the exploitation of its vast reserves of petroleum and natural gas.
"[Qatar's] ability to deliver the World Cup is totally dependent on severe exploitation of migrant labour, which we believe to be barely above forced labour conditions," said Ambet Yuson, general secretary of the Building Workers International, in May.
Developing countries, and particularly the world's least developed countries, are not only the most vulnerable to climate change; they are also often the most dependent on the exploitation of natural resources to drive economic growth.
The country is a lower middle income country and its economy and budget are largely dependent on the exploitation of gas and oil fields.
While the economy of rural areas has always been strongly dependent on natural resource exploitation, recent technological advancements in exploitation, loss of rural livelihood, and increased social demand for the amenity aspects of these resources have dramatically changed rural economies.
