We exploited the expression of MTC as biomarker to assess whether the toxic effect of AgNPs is possibly caused by the release of silver ions.
In the current work, we have exploited the expression of MMPs together with the penetration capabilities of a TAT-like peptide to engineer tumor selective adenoviruses.
We report here a targeting method that exploits the expression pattern of cell surface proteases to induce gene delivery to specific tissues.
Future work will focus on increasing expression protein levels, exploiting the expression of targeted and random mutations, and exploring the field of incorporating phylogenetically diverse enzymes into the H. jecorina secretome.
MEV based identification of sRNAs in bacterial genomes is a widely utilized approach that exploits the expression profile of sRNAs and their respective flanking regions to determine the biogenesis of sRNAs [ 53, 77, 78].
Efficacy of gene-trapping was confirmed by RT PCR and X-Gal staining of embryonic stem cell colonies (not shown) and heterozygous embryos (Fig. 4), exploiting the expression of β-geo from the trapped allele.
By exploiting the expression of epithelial cell adhesion molecule (Ep-CAM) antigen, found on the surface of primary luminal epithelial and tumour cells, we have been able to obtain near homogeneity in purifications for both cell types.
To investigate this further, we exploited the expression vector plasmid pRW224 that carries a translation initiation signal for lacZ in the vector immediately downstream of the HindIII site, and the LEE30 275 and LEE10 275 EcoRI/HindIII fragments, covering the LEE1 regulatory region, illustrated in Figure 4(A), were cloned into this vector.
Most screens, though, exploit the differential expression of imprinted genes per se.
Expression proteomics exploits the differential expression of leishmanial proteins as biomarkers for early diagnosis [ 100].
