Sentence examples for exploit interactions from inspiring English sources

Inhibitor discovery studies have focused on the active site and in particular on glucopyranose based compounds with a β-1 substituent long enough to exploit interactions with a cavity adjacent to the active site, termed the β-pocket.

Through their incorporation as monodisperse segments into synthetic polymers we learned in recent years how to program the structure formation of polymers, to adjust and exploit interactions in such polymers, to control inorganic organic interfaces in fiber composites and induce structure in biomacromolecules like DNA for biomedical applications.

It seems likely that the failure to exploit interaction with the FN2 domains is due to the fact that the FN2 domains and the catalytic domain of MMP-2 tumble independently, therefore only a tiny fraction of the conformational isomers can bind peptide hydroxamates via both the active site and the FN2 domain(s).

Immunoaffinity exploits interactions between antibodies and surface proteins of EVs to isolate EVs.

An emerging therapeutic strategy for cancer is to induce selective lethality in a tumor by exploiting interactions between its driving mutations and specific drug targets.

The second inhibitor molecule binds with the carboxyl group at the pyrimidine recognition site and the uridine moiety exploits interactions with RNase A residues Lys66, His119 and Asp121.

Two inhibitor molecules are bound in the central RNA binding cavity of RNase A exploiting interactions with residues from peripheral binding sites rather than from the active site of the enzyme.

Crystallographic analysis of these compounds in complex with GPb revealed that inhibitors with a long C5-alkynyl group exploited interactions with β-pocket of the active site and induced significant conformational changes of the 280s loop compared to GPb in complex with compounds with a short C5-alkynyl group.

A major hurdle to understanding and exploiting interactions between the stem cell and its environment is the lack of a tool for precise delivery of mechanical cues concomitant to observing sub-cellular adaptation of structure.

However, a major hurdle to understanding and exploiting interactions between the stem cell and its environment is the lack of a tool for precise delivery of mechanical cues concomitant to observation of sub-cellular structural adaptation.

By exploiting interactions between Magainin I and gram-negative bacteria and transducing those interactions into conductance changes using hRGO-based FET devices, we have demonstrated a simple and selective methodology for the detection of gram-negative bacteria that outperformed other tested carbon nanomaterials.