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And at a time when up to one-third of the world's parasite species could go extinct within a few decades – potentially opening new niches for other, invasive parasites to exploit – conservation biologists increasingly see a need to protect parasites as well as their hosts.
Additionally, we demonstrate the potential of our approach to exploit conservation information to improve the classification performance.
The second approach to exploit conservation data is to use it initially to make contact predictions and subsequently use the predictions for quality assessment.
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In contrast, D iscern makes use of the INTREPID phylogenomic conservation score (Sankararaman and Sjölander, 2008), which is able to exploit the conservation information in highly divergent datasets.
We exploit evolutionary conservation of developmental phenotypes to discover gene variants that influence brain development in humans.
Existing protein-based prediction algorithms tend to exploit evolutionary conservation when determining whether or not variants are functional.
Other algorithms exploit sequence conservation among species to determine the position of new potential genes [ 3, 4].
While many catalytic site prediction methods exploit residue conservation as a primary source of signal (Gutteridge et al., 2003; Youn et al., 2007), most of these restrict homologs to only moderately divergent sequences, limiting the effective use of this signal.
The shapes of the peaks are remarkably well conserved between WT and Resc and also between the two experiments, confirming our motivation to exploit shape conservation between replicates to increase the sensitivity of differential tests.
By exploiting its conservation properties we derive sufficient conditions for bounded solutions.
Moreover, such studies will undoubtedly advance our knowledge of the other treelines on the eastern edge of QTP and reveal common and species-specific responses to climate change that may be exploited in conservation and protection efforts.
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