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We considered two other possible explanations of the pathogenesis.
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Although this study has some limitations that may have prevented its detection, we believe that the iatrogenic dissemination theory remains one of the most likely explanations for the pathogenesis of nodal metastasis.
The activities during stimulation are all based on the resting state; it is possible that the aberrant resting-state brain activity can provide a better, direct explanation of the pathogenesis of migraine.
However the conflicting roles of THP and OPN makes the study of their reaction toward kidney stone formation also valuable for the explanation of the pathogenesis of renal oxalosis in dogs.
Several hypotheses have been arisen in the explanation of the pathogenesis of OME, which is currently thought to be an immunologic disease affected by multiple factors [ 10, 15, 16].
Neuromuscular abnormalities, in conjunction with adverse mechanical environments, in which hormonal and other chemical factors act as regulators of skeletal muscle tone and function, are possible explanations for the pathogenesis of IS [ 88].
Furthermore, studying dermal metabolic effects via metabolomics can provide novel explanations for the pathogenesis of some dermatoses and unique insights for designing targeted prodrugs, promoting drug absorption and controlling drug concentration.
Similar explanations for the pathogenesis of many picornaviruses exist.
Alternative explanations for the pathogenesis of inflammation in TRAPS have therefore been sought.
However, as early-onset AD only accounts for a few percent of AD cases and the correlation between cognitive decline and Aβ deposits is weak [ 2, 17], alternative explanations for the pathogenesis of AD have emerged [ 36, 40].
18 A variety of theories for progressive beta cell failure have been proposed as explanations for the pathogenesis and progression of type 2 diabetes.
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