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Key issues included: information and explanations, involvement in decision making, provision of advice and support, delays in care, choice, coordination of care, and practical issues (such as travel, and facilities at the hospital).
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Possible explanations include involvement of additional ErbB family members not affected by selective EGFR inhibitors, activation of other growth factor pathways such that EGFR blockade is insufficient to induce tumour regression, and changes in apoptotic components that prevent cell death in response to EGFR blockade.
A probable explanation is involvement of IgM even in some cases where only IgG or IgA is detected, since IgM will often detach from the RBC before it can be detected by DAT [ 20].
The high binding affinity for junction structures provides an explanation for involvement of XPA in both subpathways of NER and for XPA remaining on the repair complex through the late stages of NER [ 9, 22].
Second, our findings support Clarke and Cornish (2000) and Farrell et al. (1995): when looking at all places or people there may be different explanations for initial involvement in crime than repeated involvement, given the first crime.
Other interpretations and explanations for amygdala involvement are possible, however.
There are two possible explanations for metastatic involvement of arm-draining lymph nodes.
Possible explanations include the involvement of insulin in AD pathogenesis (10).
Kiebert [ 48] and Hopwood [ 49] stressed the relevance of the physician-patient relationship based on clear explanations and emotional involvement.
Even for viruses for which genome-wide screens are available SDREM's models are useful since they provide mechanistic explanations for genes' involvement in the response.
Labor's campaign spokeswoman, Penny Wong, is pushing for "a full and frank explanation of his involvement".
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CEO of Professional Science Editing for Scientists @ prosciediting.com