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When he and his colleagues analyzed tumors from the trial's patients, they found a potential explanation: variation in the amount of PD-L1 manufactured not by the cancer cells, but rather by the immune cells that had invaded the tumor.
This is clearly teleological thinking; it substitutes a goal or purpose (better adaptation to the environment) for a causal explanation (variation and differential reproductive success).
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The answer is partly familiar psychological explanations, variations on the Stockholm syndrome.
One possible explanation for variation in response to chemotherapy is genetic variation that influences gene expression and, ultimately, impacts variation in drug response phenotypes [6] [8].
An alternative explanation for variation between studies in genetic epidemiology is variation in environmental exposure between cohorts [ 14].
One possible explanation is variation in the speed of light, he said.
Contemporary geneticists offer a different explanation of variation within a species.
The charity said one explanation was variation in "stigma", which resulted in people not visiting their GP.
Based on additional surveys, we find evidence suggesting that access to credit from rural banks is an important explanation for variation in sales across villages.
Thus, the dichotomy between capital breeders and income breeders may not provide a simple explanation for variation in the relationship between maternal condition and offspring sex.
Sub-system complexity adds to the explanation of variation between developing countries.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com