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eQTL analysis is a powerful method that allows the identification of causal genomic alterations, providing an explanation of expression changes of single genes.
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The long-range regulation may provide a simple explanation of different expression patterns of similar genes (e.g. H2-T22 and - T10) and similar expression pattern of genes with distinct promoter regions (e.g. H2-T5, - T7 and - T3) over long distances.
Chris Matthews criticized Secretary of State Hillary Clinton for her explanation of her expression in the instantly iconic photo that showed her seemingly spellbound, anxious reaction during the raid that killed Osama Bin Laden on Sunday.
This generally discounts the nonlinear-constraint explanation of simultaneous expression.
One possible explanation of the expression of two Mups in OE is that these two proteins bind to odorant molecules in nasal and act as OBPs, as suggested by Utsumi et al. (1999).
The number of explanations of an expression is also called the score of this expression.
In addition, biologists have recently been asking more about the systematic explanations of gene expression patterns.
After our literature search, we gained little insight on student tendencies toward simplistic explanations of gene expression by ignoring differential gene regulation in organisms or epigenetics.
However IFNAR1−/− animals have suppressed levels of total STAT1 with respect to normal animals and this lower STAT1 has been shown to result in lower expression of STAT1-dependent genes stat1, irf1 and junB (Gough et al., 2010), providing a simpler explanation of less efficient expression of STAT1-dependent genes in IFNAR1−/− mice.
One explanation of biased gene expression could be the distance of a gene to the nearest transposable element.
These findings, taken together, support the notion that TSPY is a growth-promoting gene that increases cell proliferation in vitro and tumorigenesis in vivo, thereby providing a possible explanation of abundant TSPY expression in tumor tissues.
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