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We have provided a more detailed explanation in the Discussion section.
We have expanded this explanation in the discussion section of our revised manuscript.
Choices included genes linked to significant GO terms and pathways noted above (see further explanation in the Discussion) and genes of interest to our laboratory.
The mean serum Valproate level decreased by 26% from 512 (± 59) μmol/l for Valproate 600 mg × 2 alone to 367 (± 56) μmol/l for Valproate 600 mg × 2 combined with Buprenorphine 4 mg × 2. We think this last finding is an artefact and will offer an explanation in the discussion section.
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We discuss potential explanations in the Discussion section.
We consider possible explanations in the Discussion.
We have added a new panel to Figure 1 showing the classical song-control brain areas, and have been more generous with the explanations in the Discussion.
We speculate on a possible molecular explanation in the revised Discussion (with data provided in Figure 8).
The explanations presented in the discussion section suggest additional avenues for reducing the smoking population in workplaces, such as by considering work contexts specific to certain occupations, social norms for fostering interactions in certain sub-cultures, and the sale of cigarettes in betel-quid stalls.
However, I am still troubled by the negative Spearman coefficient values for individual sites, the authors attempt on explanation in the beginning of the Discussion notwithstanding.
Possible explanations are provided in the Discussion section.
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