Mr. Kinzer's main explanation for these recurrent misadventures is greed.
Furthermore, hyperactivity of extracellular signal-regulated kinase signaling caused by elevated levels of growth factors associated with postoperative liver regeneration enhanced the sensitivity of HCC cells to sorafenib; this provides a plausible explanation for the observation that recurrent tumors are more responsive to growth inhibition by sorafenib.
Another probable explanation for the three patients who developed recurrent disease despite negative RT PCR tests is that the recurrent melanoma was tyrosinase negative.
A likely explanation for the absence of XIST expression in recurrent ovarian cancer could be a loss of the inactive X chromosome in the tumour cells.
Another explanation for the relative dearth of evidence for recurrent hitchhiking in plants could be that forms of adaptation that do not necessarily lead to a signature of species-wide sweeps are common in plants.
Progressive fibrosis of all capsular tissues, followed by restriction of external rotation, provides an explanation for the following clinical facts, namely, that recurrent dislocation of the shoulder is seldom encountered after the fourth decade and that the malady is a self-limiting disease.
The ability of influenza virus to undergo antigenic drift by its frequent mutations allows it to cause re-infections of the same individual, and also provides one explanation for recurrent epidemics from different strains of the same influenza subtype, thus necessitating frequent updates of influenza vaccines to ensure optimal match between the vaccine and prevailing influenza strains [ 8].
The diagnosis of ADHD provided a satisfying explanation for recurrent problems, difficulties, shortcomings, and failures experienced in school, at work, or socially: "It was the answer to many years of wondering" (16).
"These findings together provide an explanation for the clinical effect of estrogen supplementation after menopause to prevent recurrent infections, as well as the high susceptibility of young women to UTI," the researchers wrote in their study.
It should also be performed when there is no plausible explanation for the mechanism of the fall, particularly if such falls are recurrent or result in serious injury.
