The secondary use of existing data is not necessarily less credible, but a statement might help to explain limitations in the study, including, but not limited to, relevant data not being assessed or the presence of peculiar population characteristics.
Interspecies differences in drug effects between animals and humans could also explain limitations in the predictive capacity of preclinical models, as quantified in previous studies (Valentin and Hammond, 2008).
Additionally, some claim that ongoing inflammatory processes in the thoracic joints may explain limitations of chest excursions, by causing pain and stiffness, and thus contributing to reduced pulmonary function [ 5, 9, 11].
The chapter also explains the limitations imposed on optical communication systems because of the pulse-broadening effects of chromatic dispersion.
The present paper explains the limitations for alternative energy technologies, with a focus on fuel cell technology development and the alternative energy sector, based on the outcomes of presentations and facilitated discussion groups during a Canadian national workshop series.
Such enhanced communication, which clearly explains the limitations of existing laboratory capacity, may help build a constituency that will aid future expansions of PHL capacity.
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