That 1991 list, called Beers Criteria, includes various sedatives, muscle relaxants, antihistamines and antidepressants, and explains their potential for harm.
This inherent ability of oligomers to promiscuously form β-linkages with a range of peptides, explains their potential toxicity.
In addition, the structural data of protein complexes suggest how oncogenic mutations influence the interactions and explain their potential impact on IL-10 signaling in cancer and inflammation.
The delayed action of progesterone derivatives on breast cancer cell growth could explain their potential differential stimulatory or growth-inhibitory effects, depending on whether the treatment is transitory or continuous, respectively [ 11- 14].
An important question regarding the long-range transport of proteins to the nucleus concerns the speed at which these messengers may travel towards the soma, which is crucial to explain their potential involvement in timely coupling of neuronal activation to the robust induction of gene programs.
(One of the executives was tasked with interrupting those who went overboard explaining their rationales). Potential providers were allowed two rounds of questioning for clarification.
For the semifinals in Boston, the Duke team had to prepare an 800-word summary, a presentation, and a short video explaining their solution and its potential impact.
The regulatory effects of donor apoptotic cells on indirect CD4 T cells explains their therapeutic potential on CAV, since in murine and pig models, CAV is initiated by CD4 T cells recognizing allo-Ag via the indirect pathway [10] [12], [70].
The sustained expression of Eomes and T-bet in IL-12/15/18-preactivated NK cells may explain their proliferative potential upon transfer into mice.
"This helps explain their high growth potential.
