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We show that allelic variants in the canine Cox-2 promoter are associated with the disease, and postulate how these DNA sequences could influence the expression of Cox-2 thereby explaining the mode of inheritance, and variable phenotype.
As well as explaining the mode of carbohydrate recognition, the structures of CL-K1 also reveal the location of residues that are altered in the 3MC syndrome (Ser, Gly and Ser).
Long-distance dispersal by wind may not be a primary factor explaining the mode of geographical distribution of Tricyrtis, considering the preferred habitats of most Tricyrtis species in wet areas and that they have no clear-cut means of wind dispersal for crossing abiotic barriers.
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Additionally, several biological experiments were performed to explain the mode of biological action.
Stoichiometry determination and molecular docking studies were also performed to explain the mode of action of compound 7.
Analysis of the optimized conformations of various adducts could explain the mode of interaction between the templates and the monomer units.
While we were able to visualize apigenin bound in one of our structures, the site was a crystal packing interface and not likely to explain the mode of inhibition.
The following subsections explain the mode of operation for each approach and describe the analytical derivation of the per-cell sum-rate throughput.
Based on our findings as well as the principle of cation exchange, a schematic representation to explain the mode of action of CML T for application in removal or reduction in the toxicity of metals present in effluents has been presented in Fig. 10.
ABFII (Aspergillus fumigatus) and CcAbf62A (Coprinopsis cinerea) are specific for α-1,2 and/or α-1,3 bonds of arabinoxylan and sugar beet arabinan, while it did not further explain the mode of action by NMR or crystal (Pérez and Eyzaguirre 2016; Hashimoto et al. 2011).
Other factors besides gp41-peptide binding can contribute to explain the mode of action of these peptides.
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