Though the people at the agency were helpful, my inquiries were typically met with general instructions, directing me to a certain form or explaining the time frame for the applications and how an IND would either be put "on hold" or "become active" within 30 days of submission.
This could be explained by the time frame of one year being too short for change to occur or by the PROMs not being responsive enough to change in a primary care sample.
This phenomenon cannot be explained by changes in human genetics because the time frame in which they have arisen or accelerated has hardly crossed a generation (Lopez and Murray 1998).
If the time frame changes, call and explain the delay.
These discrepencies could be explained either by differences in patients population or by the time frame over which the MDC was calculated.
The in-app purchase must specify the time frame the trial is being offered, and clearly explain to users what content and services it includes.
However, the time frame in which some of the therapy-resistant diseases arise cannot solely be explained by evolution under selective pressure.
The time frame also matters.
