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Most of the novel genotypes reported from the Kazakhstan National collection represent slight variants of previously described genotypes that can be explained by the insertion or deletion of >1 tandem repeats at a particular locus, usually in pX01 or pX02 (Table 3).
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This unusual behavior of the higher order peaks was explained by the lamellar insertion model of Hama and Tashiro.
The evolution of the majority of multi-domain proteins can be explained by the stepwise insertions of single domains, with the exception of repeats that sometimes are duplicated several domains in tandem.
The absence of gibbon PPP1R2P8 sequence could also be explained by the several insertions present, similar to what happens in other species, virtually dismantling it and making the retrieval impossible.
This could be explained by the smaller membrane insertion angle (closer to membrane normal) for TMD, causing less membrane perturbation.
Therefore, if the discrepancy between GC3 and noncoding GC-content had to be explained by the process of insertions and deletions, this is apparently through nontransposable-element indels.
This extreme paucity of chimeric TEs can be explained by the simple fact that TE insertions generating chimeric transcripts are likely to be strongly deleterious for the host.
The exceptional ion-exchange selectivity for ClO4− was explained by the process of dominant accumulation, quick insertion of anions, and the sluggish mobility of ClO4− inside the membrane.
We conclude that the high mean copy number in colonising Australian populations can only be explained by the presence of some sites with high insertion frequency.
According to previous studies, the presence of double peaks in the electropherograms could be explained by the presence of heterozygosity, SNPs or sequence insertions [ 20- 22].
Curiously, we found high copy-number insertions that reached up to 60; this could be explained by the presence of concatamers of the vector, rather than multiple insertions in the mouse genome.
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CEO of Professional Science Editing for Scientists @ prosciediting.com