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It is possible that discrepant findings may be explained by the duration of lithium exposure.
Our data suggest that differences between poisoning patterns regarding lithium-induced hypolocomotion are better explained by the duration of lithium exposure than by its brain accumulation.
Poor treatment response is not explained by the duration of biological effects or the specific genes induced.
The I2 statistic after accounting for pre-admission diarrheal duration shrunk from 81.2% to 48.1% indicating that a large proportion of the variability across trials could be explained by the duration of pre-admission diarrhea.
This difference can partly be explained by the duration of the illness.
Only one patient was positive for ATI, and this can be explained by the duration of infliximab treatment, 56 months [3 to 76].
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This might be explained by the duration time of stability of microbubble distribution in the hepatic sinusoid after the contrast agent injection, i.e. the ratio between the static microbubbles captured in the liver and dynamic microbubbles that are not captured but circulating in the intrahepatic vessel might vary greatly among individual subjects in the 5-min and 10-min phases.
Diabetes duration and severity and choice of anti-diabetic medication are inextricably linked and anti-diabetic drug use patterns are associated with diabetes severity and length of diabetes history; thus any differences in estimates between different exposure categories may be explained by the duration and severity of diabetes.
The high incidence of post-anaesthetic complications in the healthy group of horses (four horses with gait dysfunction, two of which showed clinical symptoms of myopathy) may be explained by the prolonged duration of anaesthesia of nearly four hours.
Mean values in the visual analog scale decreased from 2.55 at baseline to 0.95 at week 8. Analysis of objective scores, however, showed only a minor influence on hyperkeratosis, atrophy, sclerosis, and depigmentation, probably explained by the short duration of treatment of only 8 weeks.
The lack of noteworthy alterations in cardiac and renal function and structure in Alk1 +/− mice in the presence of hypertension can probably be explained by the short duration of the hypertension, because the parameters of kidney and cardiac function assessed in the present study typically do not exhibit abnormalities in hypertension until end-organ complications ensue.
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