Sentence examples for explained by a potent from inspiring English sources

This could be explained by a potent negative feedback loop triggered by combined Pml and Tsc2 inactivation that impedes further activation of nuclear Akt by loss of Pml.

Compounds 8, 9, 15 and 16 were the most potent compounds of the series, which can be explained by a similar binding mode to references indomethacin and naproxen.

These results are most easily explained by a difference in sensitivity of L. oleracea larvae to the two toxins, SflI and ButaIT, with SflI being more potent.

The high sensisitivity of most primary hematopoietic malignant cells towards MegaFasL could be explained by its potent killing effects compared with other Fas agonists.

The elevated cefotaxime MICs might be explained by the potent hydrolytic activity of CTX-M-ESBLs against cefotaxime and could be the underlying cause of therapeutic failure.

These results were explained by more potent activation of caspases and rapid cytochrome c release in MDA-MB-435 cells in response to the inhibitor compared with MDA-MB-231 cells.

These may be explained by the potent source of siRNA offered by the duplex of transfected sense Alu and Ant-alu, upon the cleavage of Dicer1, which may suppress both Sens-alus and Ant-alus depending on the guide strand directions [ 18].

The anti-angiogenic effect of ACRH and QRF could be partially explained by the potent inhibitory effect of compounds consisted in both ACRH and QRF on arachidonic metabolism through COX-2 pathway; though it is shown that both ACRH and QRF non-selectively inhibit COX-1 as well.

Our data demonstrate that LVCN is well tolerated, its intravenous administration inducing a significant delay in tumor growth and an increase in animal survival, results that can be partially explained by potent tumor apoptotic effects.

These results can be partially explained by potent tumor anti-angiogenic and pro-apoptotic effects induced by LVCN.

Simultaneous vaccination with DNA-Sm14/DNA-Hsp65 DNA-Sm14/DNA-Hsp65 DNA-Sm14/DNA-Hsp65oth experiments (Table  1), that could be explained by the less potent Th1 difailedtoation in this greducebserved by enhanced IgG1/IgG2a rathe (Additional file 1: Figure S1 and Table S1) compared to DNA-Sm14 and by the decreased IFN-γ release on bronchoalveolar space (Additional file 1: Figure S2).