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The quantitative nature of SD in fish could explain the turnover of SD systems, because genetic variation may be available in populations at loci involved in gonad differentiation, and this could allow turnover scenarios such as ones that have been modeled (van Doorn and Kirkpatrick 2010; Blaser et al. 2011).
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Upregulation of these two positive regulators may further contribute to enhanced AP of complement activation, however, subtle changes in factors B and D alone cannot explain the enhanced turnover of complement substrates [21].
To explain the slow turnover of substrates 12 and 13, we initially tested for product inhibition (see Supporting Information).
However, the rapid turnover observed for many PM proteins following exposure to heat stress seems wholly consistent with endocytic downregulation and could not be explained by the turnover of newly synthesized cargo via Golgi-to-endosome trafficking.
Intron homing might well explain the high turnover rate of introns, but it cannot explain the apparently high turnover rate of HEGs.
"Ownerships, because of the money they have invested, are too impatient," Pat Gillick said, explaining the frequent turnover of general managers.
As different variants are competing, changes in form or functions of tissues between these two species are likely to bring along changes in splicing events, explaining the high turnover of splicing events observed.
This result may partially explain the increased turnover rate of nucleosome-occupied DNA sequences observed in intergenic regions [ 19].
Multiple hypotheses have been put forth to explain the evolutionary turnover at the top of sex determination pathways.
Different mechanisms were proposed to explain the driving force for the turnover of the catalytic cycle in dehydrocoupling, hydroboration, and hydrosilylation.
The extent to which binding site turnover can explain the lack of sequence similarity between distantly related species has been difficult to assess.
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