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Although this study can not conclusively validate any of the different functional mechanisms proposed to explain the protection of haemoglobin variants, a consistently enhanced immune reactivity in both HbC and HbS adaptive genotypes suggests the idea of a convergence in terms of their impact on the acquisition of immunity against malaria.
More likely, an amplification of antigens rather than induction of a new antigen could explain the protection of anti R9 immunized rats against parental tumour metastases.
The black woman is blessed with a large bone mass which may explain the protection of Nigerian women from menopausal fracture.
A persistent insulin secretory reserve could also explain the protection of our WFS patients from significant changes in glycemia levels recorded during CGM.
Different mechanisms are suggested to explain the protection of plants by their fungal endophytes [ 49] including competition for niche occupation and resource utilization [ 43], direct interaction [ 50, 51], or induced systemic resistance [ 43, 52].
It was recently reported [ 31] that over-expression of isopentenyltransferase, an enzyme that catalyzes the rate-limiting step in cytokinin biosynthesis, causes an elevation in cytokinin-dependent photorespiration, which can explain the protection of photosynthetic processes beneficial during water stress [ 31].
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A novel equivalent circuit model, which takes into account the inductive effect arising from the generation of corrosion products on the steel bar surface, is proposed to explain the protection performance of the microcapsules against the corrosion of a steel rebar in a concrete.
Regarding policies in India for the unorganized sectors, there are the Factories Act, 1948, and the Building and Other Construction Workers (Regulation of Employment and Conditions of Service) Act, 1996, but none of these policies clearly explain the protection or rights of these female workers regarding their occupational health and safety.
This however does not fully explain the protection in the absence of GSH, therefore stabilization of other parameters should be considered, such as decreased apoptotic factors and protection against lipid peroxidation.
The latter observation may partly explain the protection against muscle atrophy through suppression of FOXO3-mediated induction of the atrogenes MuRF-1 and atrogin-1 (Sandri et al., 2006).
Finally, the nocturnal activity of NPH insulin indicates a peak of between 0100 and 0400 h, whereas glargine is peakless and detemir increases its activity overnight slowly after an initial lag phase (40), thus explaining the protection against risk of nocturnal hypoglycemia of the two analogs compared with NPH in clinical studies (32).
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