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Several factors have been proposed to explain the poor penetration and distribution of GNPs in solid tumors.
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Impaired drug penetration into hypoxic regions of tumours was thought to explain the poor prognosis, but recently an adaptive cellular response to hypoxia was demonstrated to reduce the cytotoxicity of many drugs.
Three factors explain the poor showing.
The panel sought to explain the poor performance.
Dosimetry results explain the poor clinical benefice observed.
Those explain the poor hygiene behaviours.
Lung infection has been identified as an independent predictor of treatment failure in MRSA bacteremia treated with vancomycin and not explained by MIC [ 52], perhaps reflecting the poor penetration of this antibiotic into the lung tissue [ 53].
This variability can be explained by the low quality of bonding, generated by the poor penetration of the adhesive into wood as well as the incomplete polymerization under pressure, where small force variations supported by the body of evidence of this treatment resulted in high death rates.
There are, however, technical problems, including the poor penetration of light into deep tissues.
Technologies such as fluorescent proteins and optogenetics serve this purpose in small, translucent specimens, but are limited by the poor penetration of light into deeper tissues.
Various factors are responsible for the poor penetration of topical and systemic antibiotics in the vitreous.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com