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This is highly relevant, among others, in attempts to create synthetic life forms in genetic isolation by using tailored "minimal genomes" and may explain the necessity for multiple coding evens in nature.
Central activation of CB1 mediates the rapid effect of glucocorticoid negative feedback and this might explain the necessity for high peripheral doses of the CB1 antagonist rimonabant to increase cortisol levels [ 120, 121].
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Vincent Giesegh, Kirsten's father, told KKTV in a recent interview, that although they have tried to explain the necessity of the ramp for their daughter's safety, their neighbors have not changed their mind.
Postulating that length of the ExCh molecule is critical for its efficiency, would explain the necessity of a close framing of the exon to be replaced.
CEOs need to be ready to explain the necessity of the shift.
There are two main points that explain the necessity of the investigation in this study.
Likewise, explain the necessity of using a fork when eating pasta.
A PARAGRAPH in the preface to this new edition of Prof. Clifford Allbutt's great "System of Medicine "sufficiently explains the necessity for a revision.
The newly inferred edges ErbB-3 →ErbB-1 and cJUN →ErbB-1 in HCC1954 explained the necessity for erlotinib against ErbB-1 dimers.
Although course tutors provided letters for GPs explaining the necessity for these adjustments, interviewees reported having to be 'quite tough' to successfully negotiate with primary care teams who were reluctant to absorb the rise in short-term costs.
Importantly, inhibition of the mevalonate pathway prevents the activation of the UPRmt in normal worms, which explains the necessity for UPRmt-activating mutations to achieve resistance (Ranji et al. 2014; Liu et al. 2014).
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