This deficit can therefore explain the impairment in transmitter release at the presynaptic terminals without, however, excluding the possibility that the impaired transport of other cargoes is also involved.
Delayed platelet activation may explain the impairment in fibrin formation reported in DIC.
More targeted and functional studies of the blood-brain barrier, including investigation of its subcomponents, are now required, and further investigation is necessary to determine whether, if proven, blood-brain barrier dysfunction can directly explain the impairment in glucose utilization in the brains of schizophrenic patients.
Several possibilities might explain the impairment in PKCε translocation in the OxP group.
A reduction in beta cell mass may help explain the impairment in maximal secretory capacity for insulin.
Because the monkeys tested by Turchi et al. (2005) only encountered extended delays and list lengths postoperatively, this could explain the impairment observed in their study and the intact performance in monkeys in our study.
In light of the magnitude of load asymmetry that occurs following THA [ 24], however, this effect is likely too low to explain the impairment in postural control observed in the current study [ 25].
These calculations show that these relatively low numbers of cumulative cellular ablations do not disconnect or disintegrate the core CPG, which suggests that a breakdown in network structure cannot explain the impairment and cessation of rhythmic function.
In nonobese patients (BMI <30 kg/m), reductions in DLCO, DLNO, and VC were fully explained by the lower lung volume and peak Q̇, but these factors did not fully explain the impairment in obese patients (BMI >30 kg/m).
The direct effect of progesterone on amygdala function already discussed may explain the impairment of memory associated with the premenstrual phase and pregnancy, 23 and cognitive function has certainly been shown to decline around the time of and after the menopause.
