Apart from the detrimental effect of even mild hyperglycaemia on bacterial defences, and wound healing and repair after ischaemia/reperfusion [ 11], there are various other potential mechanisms to explain the harmful effect of hyperglycaemia.
© UNICEF/NYHQ2009-2242/Khemka A community educator explains the harmful effects of child marriage to a group of women and girls in Jodhpur.
Teachers suggested direct punishment, education, persuasion, explaining the harmful effects of alcohol, and reporting students' bad behavior to their parents as ways to prevent alcohol-related problems.
In relation to specific activities, the most frequently performed were those that could be done in a short period of time--asking about tobacco, advising to quit, explaining the harmful effects, encouraging/motivating patients to quit, and suggesting NRT, actions to cut down, and smoking alternatives (Table 3).
At least two mechanisms are identified to explain the potential harmful effects of this host inflammatory response: cytokines have the capacity to damage the cells (cytotoxic effects) [ 3], and the prolonged release of inflammatory mediators leads to severely impaired immunity [ 4].
However, in undertaking this research, investigators must not forget that their primary goal is to find effective ways to manage a pandemic in populations and not simply to explain in more precise terms the harmful effects of pandemic virus infection in individuals.
The rapid rising in pressure can be a factor that explains the potential harmful effects of the RM.
If that was all explained very clearly then, including the harmful effects it might have – that's the research, of course – then I'd join more easily.
This raises the possibility that the harmful effects of amyloidogenic processing are mediated by both increased Aβ as well as elevated AICD (Fig. 6E) and may explain the disappointing results from Aβ-focused Aβ-focusedrials.
