We next sought to explain the gain-of-function phenotype of the FLL mutant.
Unlike intron homing, gene conversion can explain the gain of HEG associated with the mosaic intron sequence in T. delbrueckii.
This would explain the gain of negative charge (two sulfonate groups) and molecular mass (eight oxygen atoms) leading to the observed electrophoretic mobility and molecular weight.
Several mechanisms have been invoked to explain the gain of novel gene function for duplicated genes such as dosage compensation, epigenetic complementation, moonlighting, and catalytic promiscuity [ 12- 17].
This would explain the gain of function property of SecTRAP enzymes and could explain their deleterious effects, possibly via the increased NADPH oxidase activity as reported by Arnér and co-workers.
Note that plant S10, S13 and S20 protein sequences are much longer than their prokaryotic counterparts (see in Additional file 8: Table S7), and this might explain the gain of disordered segments.
On the other hand, however, we cannot preclude that differences in rRNA composition between chloroplast (23S, 5S and 4.5S) and bacterial (23S and 5S) large 50S ribosomal subunit could also explain the gain of disorder observed in this subunit [ 43, 44].
Therefore, we have benchmarked the processors using the STREAM benchmark (data-intensive application) and we have observed that, in practice, the 7250 attains a memory bandwidth that is about 2.7 × higher than the 7120P, which explains the gains of the Bloomfwd with the 7120P.
According to Langley and Jackson [ 29], low-protein intake induces intrauterine protein restriction during diet that could explain the gain (in grams) of placenta and fetuses in P. reticulata treatment.
