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Such an effect may also explain the disruption of the epithelial barrier.
The loss of this effect may partly explain the disruption in circadian rhythm of cortisol synthesis during sepsis.
Purely theoretically, based upon the mechanisms outlined above, numerous hypotheses can be advanced to explain the disruption of sleep in the elderly.
The presence of dead cells within the epithelium and reduced delamination could explain the disruption of gut barrier integrity observed in flies with reduced EGFR activity in enterocytes.
This would explain the disruption of MreB filaments by A22 as reported previously (Bean et al., 2009; Dye et al., 2011).
Such deregulated Rac activity may partially explain the disruption of cell-cell and cell-matrix adhesion and tumor dissociation, which characterize this invasive and highly metastatic model (Morton et al., 2010, Muller et al., 2009, Muller et al., 2013).
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Besides, this last point and the search of other mechanisms explaining the disruption of these interactions are two ongoing subjects of study in our lab (referred as "X event" in figure 9).
WASHINGTON — American Airlines and the Federal Aviation Administration, endeavoring to explain the biggest disruption to air travel in years, disagreed on the fundamental facts in reports each submitted to the federal transportation secretary.
In both hypotheses, shearing biomechanical forces are thought to drive the development of dissecting lesions and biomechanical influences may explain the local disruption of cartilage canals as well as the existence of predisposition sites [ 9, 11, 16].
Multiple models have been proposed to explain the chronobiological disruptions associated with bipolar disorder (Gonzalez 2014).
The deteriorating process described above is consistent with claim #3 in section 2. The mathematical theory introduced in this paper unveils an underlying mechanism that may explain the deterioration and disruption occurring massively in sentimental relationships that were initially planned to last forever.
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