Exact(4)
Moreover, the four-rung β-solenoid architecture provides a molecular framework for an autocatalytic propagation mechanism, which could explain the conversion of PrPC into PrPSc.
To explain the conversion of proteins from soluble to fibrous forms, several types of models have been proposed: refolding, natively disordered and gain of interaction.
DI particles have been observed most commonly in vitro during serial passages of viruses at high multiplicities of infection, and often have been invoked to explain the conversion of acute in vitro infections to persistent ones [6] [11].
The location of the CTI gene in a rapidly evolving region of the eutherian chromosome [ 51, 62] may explain the conversion of CTI into a putative pseudogene in Afrotheria (elephant), Xenarthra (sloth, armadillo), Euarchontoglires (humans, primates, rodents) and in selected Laurasiatherians such as the horse and flying fox.
Similar(56)
In 1967, applying to Indiana U Law School, I had to travel there and explain the conversion chart on the back of my transcript.
We will explain the conversion procedure here.
When taken together these provide for a prion-like mechanism that can serve to explain the observed conversion of wtSOD1 to a misfolded form by the G85R mutant.
This unusual behavior can be explained by the conversion of the nitro group present in the NPFASC molecule into amino group on approaching the metal surface in the corrosive medium.
The pH reduction could be explained by the conversion of acetoin to acetate catalyzed by AoDH ES [2].
The reduced level of pmpD expression at late and very late time points after infection (30 48 hours) could be explained by the conversion of most RBs to infectious EBs, in which little pmpD expression occurs.
The apparent higher serological prevalence using the plate test could be explained by the conversion of fibrinogen to fibrin, which can lead to false positive results [ 27]; cross reactivity with antibodies to other gram negative bacteria could be an alternative explanation.
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