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When comparing data derived from different databases, non-ACGT content was found to explain a significant component of pool coverage (see additional file 4).
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In a two-level hierarchical AMOVA (Table 2), neither ITS nor NifD sequence explained a significant component of variance between host species within genus.
In this paper, we present a regulatory network model (TOM) that explains a significant component of the unexpected low frequency of IC changes in expression levels between mRNAs and their regulating miRNAs.
The analysis showed that the difference between adapted and mismatched parasites explained a significant component of the variation of the parasites' infectivity (P < 0.001), confirming that the parasites had indeed evolved to be more infectious on the isofemale line they had evolved on.
Although the first two principal components explain a significant amount of the variation in both datasets, only the Golub model performs well when cross-validated.
Components that do not explain a significant amount of variation should not be analysed and interpreted since they may mainly describe noise.
As seen previously [9], [11], components associated with gene expression explain a significant percent of the variance in the dataset.
Including these components in clustering or multivariate analyses allows us to remove components that are likely driven by noise and to concentrate on those which, individually, explain a significant fraction of the data variability (i.e. 90%).
Interestingly, genome size did not explain a significant amount of the deviance in the total fractions of ORFs (p in Eqs. 1 2) described by the random components of the mixture models (F = 2.36, p = 0.06; Fig. 3c).
We conclude that a significant component of century-scale variability in Yucatan droughts is explained by solar forcing.
The PCA identifies orthogonal components explaining a significant (e.g. 90%) fraction of the variance.
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