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In that study, introductory students answered an open-ended question that required them to consider whether genetic drift could explain a shift in genotype.
As reported in this issue of Aging by Nakamura et al, age-related resistance of skeletal muscle-derived progenitor cells to SPARC (an autocrine differentiation factor) may explain a shift from myogenesis to adipogenesis (Aging 2012; 4: this issue).
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Ben Elliot, the boss of Quintessentially Group, a concierge service that helps the rich organise their lives, is explaining a shift in the way that money is raised for charity.
The neighborhood, once almost entirely black, is now mostly Latino, Nix explained, a shift that happened across south L.A. as immigrants came up from Mexico and black families left for the inland suburbs.
A20 Gore on Social Security Vice President Al Gore, explaining a shift in his position, said the stock market was an attractive place for Americans to invest over the long run but not for seeking a solution to Social Security's problems.
Now Empires of the Imagination sets out to explain a parallel shift: how did Britain go from "relative artistic backwater" to the "leading cultural power in Europe"?
An unexpected hike in interest rates by the Federal Reserve might explain a dual shift, but the last Fed statement hardly suggested the America's central bank was in a hurry.The alternative explanations get quite convoluted, but fairly represent the complex world in which financial traders use a combination of leverage, hedges and diversified positions.
The change in marker sets from the initial exposure to a largely intracellular survival strategy may explain a corresponding shift in the marker sets observed in this study.
In addition, this situation would more likely explain a vertical shift, for instance from the medial femoral condyle to the medial tibial plateau, rather than a horizontal migration from medial to lateral.
There is no evidence of a consistent reduction in the firing rate of motor neurons after stroke (Pierrot-Deseilligny and Burke, 2005) to explain a significant shift to lower frequencies.
Such a dose variation might explain a non-uniform shift of metric response distributions, in our case BMI, which cannot be assessed by using binary variables for originally continuous exposures.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com