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These are the two cases in which we feel confident in asserting a common function between two proteins; the first reflects an expert assertion, and the second an instance in which divergence is minimal.
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The more comprehensive and well structured the collection of expert assertions, the more rapidly accurate projection technology will be developed.
On the other hand, there is every reason to believe that fully automated tools can be developed to project these expert assertions.
One technology for creating and maintaining expert assertions was developed within the context of The Project to Annotate 1000 Genomes [ 10].
2. Bioinformatics tools are developed to project structured collections of expert assertions (rather than just the wet lab results captured in the literature) to new genomes.
The process of integrating what is known from the literature into a set of expert assertions involves highly complex decisions and is well beyond most of the common bioinformatics tools.
In an initial stage, an expert in a biological topic integrates what is known from the literature producing a set of expert assertions, which include the assertions from the literature, as well as a far broader set based on judgement and extrapolation.
Here it is worth noting that we speak of "well-structured" sets of expert assertions, since the developed tools will almost certainly need to encapsulate numerous rules covering special cases, and a careful delineation of these rules can best be achieved by domain experts.
As for your expert's assertion about the acuity of sharks' eyesight, it doesn't take into account the turbidity of water or the time of day.
Morrison, 38, who has often derided conventional views on H.I.V. and AIDS, said he was pleased to hear some experts supported his assertion of a false positive.
Some experts challenge the assertion that fear of punitive strikes has deterred countries from using poison gas.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com