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In addition, some truncation experiments of domain C suggested that the enzyme activity, as well as stability, was not influenced by the removal of part of the domain [ 45, 46].
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In contrast, foot-printing experiments on domain V of 23S rRNA showed specific and identical protection sites with both 6AP and GA but not with their inactive derivatives (right panel).
In our experiments of predicting domain functions, we used Arabidopsis thaliana, Saccharomyces cerevisiae, and Homo sapiens as benchmarks.
Furthermore, comparison of NMR titration experiments of PWWP domain with either a native H3K36me3 or a H3KC36me3 peptide showed that peptide binding affects the same PWWP residues in a highly similar manner.
By gene disruption experiments of a dehydratase domain of module 12 and an FkbH-like protein, this gene cluster was confirmed to be involved in the biosynthesis of bafilomycin.
In Experiment 3, a manipulation of error-weighting replaced the manipulation of domain (Experiment 1).
It contains the atomic workflows that implement basic Quantum Chemistry operations and can be used in scientific experiments of different sub-domains in QC.
Deletion experiments of individual ACP domains in the mupirocin cluster revealed reduced activity for the pathway [46].
23 Denaturant (GdmCl -induced equilibrium and kinetic (un)foldinGdmCl -inducedof singlequilibriumands were determined using a Cary Eclipse fluorimeter, with 2 μ m protein in phosphate-buffered saline (PBS; 10 m m sodium phosphate (pH 7.4), 137 m m NaCl, 2.7 m m kineticd 5 m m 1,4-dithiothreitol (DTT) at 25 °C.
In the second set of experiments, domain knowledge was used to perform sensible initialization.
Experiment 4 tested effects of domain knowledge and found, surprisingly, that even some learners with high domain knowledge initially constructed the incorrect mental model.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com