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Please note that while additional experiments are not specifically being requested in the revision, helpful further experiments have been indicated in specific comments below, and major revisions are being suggested.
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To compare theory and experiment, computer experiments have been performed which indicate that the time dependence of the coefficients in a general dispersion equation may be quite complex.
A minor fact let for the discussion on page 12: in vitro RNA selection experiments have been published that indicate ribozymes can perform aminoacylation (Lee, N., Bessho, Y., Wei, K., Szostak, J.W., and Suga, H. 2000. Ribozyme-catalyzed tRNA aminoacylation. Nat. Struct. Biol. 7: 28 33).
Since the effects of Net1 specific shRNA or siRNA were reproducibly similar, the results of Net1 knock down experiments have been summarized together and are henceforth indicated as iRNA.
Unless otherwise indicated, all experiments have been performed independently at least three times.
Thus far, their website - 'Inventory of Human Xenotransplantation Practice' - has collected data on 34 clinical trials.7 The inventory indicates that xenografts experiments have been performed in Europe, North America, Africa, Asia and the Pacific.
The figure legends do not indicate how many times these experiments have been performed.
Comprehensive experiments have been conducted on the specified platform using different groups of sequences selected from the indicated datasets.
Other experiments have been even more dramatic.
A scientist planning experiments checks the abstracts to see what similar experiments have been performed.
In vitro experiments had been published indicating that 5-HT7 receptors are involved in mediating 5-HT actions in the mammary glands [ 15, 18, 20, 21].
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