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We discuss internal validity in terms of threats to our experiments designs.
We propose the Cognitive Walkthrough (CW) as an aid to improve experiments' designs.
New experiments' designs are based upon data gathered from prior models.
The experiments designs were as follows: 1) Four months old zebrafish were divided into three groups consisting of 8 fish in each group: i) adult spermeating males weighing 2.45 ± 0.207 g (N = 8) were exposed to E2 (Sigma-Aldrich, USA) by immersion for 48 hr (group E2-treated males).
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The 2014 vaccine study was part of a series of experiments designed to answer the question.
Physiological experiments designed to test this hypothesis would be challenging.
TMO performed laboratory experiments, designed experiments, and drafted the manuscript.
MGJ conducted the experiments, designed the experiments and analyzed data.
AC performed experiments, design the study and analysed data.
PJK performed experiments designed the study and modified the manuscript.
Experiments designed to address this question have yielded mixed results.
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