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TFBS data from RegulonDB is supported by literature with experimental evidence; in the majority of cases this evidence stems from classical experimentation such as DNA footprinting and/or site mutation expression analysis and is not supported solely by human or computational inference.
On the fringes, things are as noisy and glitchy as ever, with hubs of experimentation such as Music Hackspace and Cafe Oto in London.
And Kim Jong-il consistently threatened to freeze small pockets of openness and experimentation, such as the Kaesong Industrial Complex free-trade zone with South Korean companies, whenever political problems arose with Seoul.
One way to counteract the HiPPOs is to cultivate a culture of objective experimentation, such as A/B testing.
Lee Worden explains what is amiss with this very Californian, techno-libertarian ideal of 'do-ocracy': "In hacker circles and other Petri dishes for cultural experimentation such as Burning Man, the word 'do-ocracy' has become popular.
A huge amount of data on each compound is required, and alternative methods to direct experimentation such as in silico models are listed as possible sources of this information.
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Hence, the biological usefulness and effectiveness of these miRNAs for the inhibition of H5N1 replication in chicken needs to be evaluated further by biological experimentations such as in vitro virus challenge and luciferase reporter assays, etc.
A common practice in scientific experimentation in areas such as Medicine, Pharmacy, Nutrition, among others, is to measure each sample unit three times (in triplicate) or more generally, m times (in m plicate) and take the average of such measurements as the response variable.
We note that further experimentation using methods such as cross-linking and sequential CoIP can improve the detection process, but is far more costly.
Experimentation has brought innovations, such as comment threads, and the ability to mix thoughts, pictures and links in a stream, with the most recent on top.
Like that novel, this one acknowledges the brio and experimentation of American writers such as Thomas Pynchon or Don DeLillo or the late David Foster Wallace; it takes on board some of the philosophical caveats to "conventional" social realism, but does it anyway.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com